A dual kinase inhibitor* is entering a clinical trial for advanced pancreatic cancer in combination with gemcitabine as part of Cancer Research UK’s Combinations Alliance. The novel combination of drugs targets the process of nerve invasion, observed in over 80% of pancreatic ductal adenocarcinoma (PDAC) and is associated with tumour spread and…...
Cancer drug approved for NHS use in England gives some multiple myeloma patients another option
A drug has been made available on the NHS in England for adults with a type of blood cancer called multiple myeloma who cannot receive standard treatment. They say the decision will benefit approximately 2,100 patients a year. Read more at: https://www.cancerresearchuk.org/about-us/cancer-news/news-report/2019-05-17-cancer-drug-approved-for-nhs-use-in-england-gives-some-multiple-myeloma-patients-another-option...
Bowel cancer rates are rising in young adults, but do we know what’s behind the increase?
Bowel cancer rates are increasing in adults aged between 20 and 50, according to data from 2 big studies published this week. Both studies looked at large numbers of people across several countries, including the UK, providing strong evidence on the number of people developing bowel cancer. And some worrying trends emerged.…...
News digest – bowel cancer rates, brain tumour ‘pink drink’, cigarette displays and chewing gum
Grace Li New from News Digest this week: follow with new breakthroughs and research on bowel cancer rates, brain tumor “pink drink”, cigarette displays and chewing gum. Read more at: https://scienceblog.cancerresearchuk.org/2019/05/18/news-digest-bowel-cancer-rates-brain-tumour-pink-drink-cigarette-displays-and-chewing-gum/...
New therapeutic avenue in the fight against chronic liver disease
Chronic liver disease is known as the silent killer, showing no obvious symptoms until the disease has progressed to an advanced stage. Therefore, making a proper diagnosis in the early stage of disease progression a clinical challenge. An international team of researchers, affiliated with UNIST, has identified a novel route that regulates the…...
Molecular profiling could catch lung cancer early and lead to new treatments
Before lung cancer develops, precancerous lesions are found in the airway, but only some of these will actually become lung cancer, while others will disappear or remain benign without becoming harmful. Under the microscope, the lesions look the same, making it difficult to know which lesions to treat. A new…...
Antibodies to a retina protein to be used as a kidney cancer marker
Tumors can be benign or malignant. Benign tumors can evolve into malignant ones. Around 90 to 93% of all kidney growths turn out to be malignant, and there are currently no effective methods for early diagnostics. The initial stages of kidney cancer have no signs or specific symptoms, so patients are often…...
What happens if chemotherapy does not work?
Chemotherapy is used by doctors to either as a first-line therapy or in combination with other treatments, such as surgery, to treat cancer. If chemotherapy does not work, a person may need to consider other treatment options. Signs that the cancer is not responding to chemotherapy include the growing or spreading…...
DNA origami: A precise measuring tool for optimal antibody effectiveness
Using DNA-based designs of precise nanostructures — scientists have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system. The study may be of significance to the development of vaccines and immunotherapy used in cancer.…...
